Research


Publications

Inflammatory Breast Cancer: Clinical Implications of Genomic Alterations and Mutational Profiling

FLC Faldoni, RAR Villacis, LM do Canto, CE Fonseca-Alves, SS Cury, SJ Larsen, MM Aagaard, CP Souza, C Scapulatempo-Neto, CABT Osório, J Baumbach, FA Marchi, SR Rogatto

Cancers, MDPI, 2020

DeepCLIP: predicting the effect of mutations on protein–RNA binding with deep learning

AGB Grønning, TK Doktor, SJ Larsen, USS Petersen, LL Holm, GH Bruun, MB Hansen, A Hartung, J Baumbach, BS Andresen

Nucleic Acids Research, Oxford University Press, 2020

De Novo and Supervised Endophenotyping Using Network-Guided Ensemble Learning

SJ Larsen, HHHW Schmidt, J Baumbach

Systems Medicine, Mary Ann Liebert, 2020

Increased levels of genomic instability and mutations in homologous recombination genes in locally advanced rectal carcinomas

LM do Canto, SJ Larsen, BEC Kupper, MDF de Souza Begnami, C Scapulatempo-Neto, AH Petersen, MM Aagaard, J Baumbach, S Aguiar-Jr, SR Rogatto

Frontiers in Oncology, Frontiers, 2019

Genomic profiling in ovarian cancer retreated with platinum based chemotherapy presented homologous recombination deficiency and copy number imbalances of CCNE1 and RB1 genes

AABA Costa, LM do Canto, SJ Larsen, ARG Ribeiro, CE Stecca, AH Petersen, MM Aagaard, L de Brot, J Baumbach, G Baiocchi, MI Achatz, SR Rogatto

BMC Cancer, Springer Nature, 2019

Comprehensive genomic profiling of androgen-receptor-negative canine prostate cancer

R Laufer-Amorim, CE Fonseca-Alves, RAR Villacis, SAD Linde, M Carvalho, SJ Larsen, FA Marchi, SR Rogatto

International Journal of Molecular Sciences, MDPI, 2019

From single drug targets to synergistic network pharmacology in ischemic stroke

AI Casas, AA Hassan, SJ Larsen, V Gomez-Rangel, M Elbatreek, PWM Kleikers, E Guney, J Egea, MG López, J Baumbach, HHHW Schmidt

Proceedings of the National Academy of Sciences, National Academy of Sciences, 2019

The Selection of a Hepatocyte Cell Line Susceptible to Plasmodium falciparum Sporozoite Invasion That is Associated With Expression of Glypican-3

RE Tweedell, D Tao, T Hamerly, TM Robinson, SJ Larsen, AG Grønning, AM Norris, JG King, HC Law, J Baumbach, ES Bergmann-Leitner, RR Dinglasan

Frontiers in Microbiology, Frontiers, 2019

E. coli gene regulatory networks are inconsistent with gene expression data

SJ Larsen, R Röttger, HHHW Schmidt, J Baumbach

Nucleic Acids Research, Oxford University Press, 2018

CoNVaQ: a web tool for copy number variation-based association studies

SJ Larsen, LM do Canto, SR Rogatto, J Baumbach

BMC Genomics, Springer Nature, 2018

CytoMCS: a multiple maximum common subgraph detection tool for Cytoscape

SJ Larsen, J Baumbach

Proceedings of the 2017 International Symposium on Integrative Bioinformatics, De Gruyter, 2017

A simulated annealing algorithm for maximum common edge subgraph detection in biological networks

SJ Larsen, FG Alkærsig, HJ Ditzel, I Jurisica, N Alcaraz, J Baumbach

Proceedings of the 2016 on Genetic and Evolutionary Computation Conference, ACM, 2016